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Sym 004

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Area
  • HY-P99306

    DS 1024; Sym 004

    Inhibitory Antibodies Cancer
    Modotuximab (Anti-Human EGFR Recombinant Antibody) is an IgG1κ-type chimeric antibody targeting human EGFR protein. Modotuximab contains a portion of Futuximab that binds to two independent, non-overlapping epitopes on EGFR. Modotuximab promotes cross-linking of EGFR on the cell surface and promotes EGFR cellular internalization and degradation. Modotuximab has antitumor activity in vivo .

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